Home > Uncategorized > NEW RESEARCH-Damaged disc loses glycosaminoglycan

NEW RESEARCH-Damaged disc loses glycosaminoglycan

Spine (Phila Pa 1976). 2011 Aug 15;36(18):1438-45.

Mechanical deformation and glycosaminoglycan content changes in a rabbit annular puncture disc degeneration model.


* Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana † Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California.

For some time, the glycosaminoglycan content of the disc is well-documented. A set of researchers set out to find out for sure what happens to the glycosaminoglyan content when the disc is damaged.
Researchers punctured the lumbar spine’s anulus fibrosus.

They performed an MRI after 5 weeks to estimate the disc volume and glycosaminoglycan distribution.

The disc volume increased significantly at 4 weeks after the puncture. The nucleus pulposus (center of the disc) displaced from anulus fibrosus (outer rings of the disc) increased T1 weighting of disc and glycosaminoglycan significantly decreased.

So this all shows that if there is damaged disc, the glycosaminoglycan escapes the damaged disc, and the disc itself changes. What could help the disc? Possibly nutrition and chiropractic flexion distraction?

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